Thermo Fisher Scientific Septin 2 Polyclonal Antibody
Western blot 및 IHC(P)에서 검증된 Rabbit Polyclonal 항체로, Human 및 Mouse에 반응합니다. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공됩니다. 세포골격 GTPase인 Septin 2 단백질 연구에 적합합니다.
- 카탈로그번호
- PA527485
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–175 of Human Septin 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 40% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2544961 |
Product Specific Information
- Recommended positive controls: NT2D1, IMR32, Jurkat, HeLa
- Predicted reactivity: Mouse (99%), Rat (98%), Zebrafish (93%), Xenopus laevis (91%), Pig (98%), Bovine (98%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Septin 2 is a filament-forming cytoskeletal GTPase required for normal organization of the actin cytoskeleton. It plays a role in epithelial cell polarization by maintaining polyglutamylated microtubules, facilitating vesicle transport, and preventing MAP4 binding to tubulin. Septin 2 is essential for mitotic progression, spindle organization, and chromosome congression. It also contributes to chromosome segregation, spindle elongation, ciliogenesis, and collective cell movement.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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