Thermo Fisher Scientific MyD88 Polyclonal Antibody
MyD88 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC에 사용 가능. 인간, 마우스, 랫트에 반응하며 항원 친화 크로마토그래피로 정제됨. 염증 반응 연구 및 신호전달 경로 분석에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.5–2 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 10–20 µg/mL | - |
| Immunocytochemistry (ICC/IF) | 10–20 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A peptide corresponding to 17 amino acids near the carboxy terminus of human MYD88 isoform 1. The immunogen is located within the last 50 amino acids of MYD88. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11154287 |
Product Specific Information
- Suggested positive controls: A431, A549, K562, HepG2, or NIH/3T3 Cell Lysates
- Blocking peptide: PEP-0045
- Predicted molecular weight: ~35 kDa
- In Western blot, observed band at 35 kDa
- Predicted species reactivity based on immunogen sequence:
- Pig: 94%
- Sheep: 82%
- Bovine: 82%
- Chicken: 82%
- Avoid prolonged exposure to high temperatures
Target Information
Myeloid differentiation Marker 88 (MyD88) is an adaptor molecule for the Toll/IL-1R and is involved in the inflammatory response induced by IL-1, IL-18, and LPS. MyD88 recruits IRAK to the IL-1 receptor complex in response to IL-1, leading to activation of NF-κB. MyD88 is widely distributed across tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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