Thermo Fisher Scientific MyD88 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.5-2 µg/mL

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Immunohistochemistry (Paraffin) (IHC (P))

10-20 µg/mL

-

Immunocytochemistry (ICC/IF)

10-20 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A peptide corresponding to 17 amino acids near carboxy terminus of human MYD88 isoform 1. The immunogen is located within the last 50 amino acids of MYD88. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MyD88,uniProtId:Q99836-1,ncbiNodeId:9606,antigenRange:296,antigenLength:296,antigenImageFileName:PA5-19919_MyD88_Q99836-1_Rabbit.svg,antigenImageFileNamePDP:PA5-19919_MyD88_Q99836-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.02% sodium azide

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_11154287

Product Specific Information

Suggested positive controls are A431, A549, K562, HepG2, or NIH/3T3 Cell Lysates.

PA5-19919 can be used with blocking peptide PEP-0045.

Predicted molecular ~ 35kD. In Western blot applications, this antibody has been observed to detect a band at: 35kD

Predicted species reactivity based on immunogen sequence: Pig: (94%), Sheep: (82%), Bovine: (82%), Chicken: (82%)

Antibodies should not be exposed to prolonged high temperatures.

Target Information

Myeloid differentiation Marker 88 (MyD88) is an adaptor molecule for the Toll/IL-1R and is involved in the inflammatory response induced by IL-1, IL-18 and LPS. MyD88 recruits IRAK to IL-1 receptor complex in response to IL-1. This pathway further leads to activation of NF-kB. MyD88 has a wide tissue distribution.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.