Thermo Fisher Scientific Thymidine Phosphorylase Polyclonal Antibody
인간 Thymidine Phosphorylase를 인식하는 Rabbit Polyclonal Antibody로, WB 및 ICC/IF에 적합. 항원 친화 크로마토그래피로 정제되었으며 액상 형태로 제공. 4°C 또는 -20°C에서 보관 가능하며 연구용으로 사용.
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Thermo Fisher Scientific Thymidine Phosphorylase Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TYMP. Recombinant protein control fragment (Product #RP-91382). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.30 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2789037 |
Product Specific Information
Immunogen sequence:
EGSQGLPDPS PEPKQLPELI RMKRDGGRLS EADIRGFVAA VVNGSAQGAQ IGAMLMAIRL RGMDLEETSV LTQALAQSGQ QLEWPEAWRQ QLVDKHSTGG VGDKVSLVLA PALAACGCKV PMISG
Target Information
Thymidine phosphorylase (TP), also known as platelet-derived endothelial growth factor (PD-ECGF) or gliostatin, catalyzes the reversible phosphorolytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate in the presence of inorganic orthophosphate.
It acts as a chemotactic and mitogenic factor for endothelial cells and serves as a non-heparin binding angiogenic factor present in platelets.
TP is also involved in the transformation of fluoropyrimidines, cytotoxic agents used in cancer treatment, into active metabolites.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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