Thermo Fisher Scientific BHLHB5 Polyclonal Antibody
인간 BHLHB5 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 시약으로 안정적인 신호 검출 제공. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,500–1:5,000 |
| Immunocytochemistry (ICC/IF) | 1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human BHLHB5. Recombinant protein control fragment (Product #RP-103577). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.16 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2638547 |
Product Specific Information
Immunogen sequence:
EDDLFLHKSL SASTSKRLEA AFRSTPPGMD LSLAPPPRER PASSSSSPLG CFEPADPEGA GLLLPPP
Highest antigen sequence identity to the following orthologs:
- Mouse: 91%
- Rat: 93%
Target Information
BHLHB5 inhibits DNA binding of TCF3/E47 homodimers and TCF3 (E47)/NEUROD1 heterodimers and acts as a strong repressor of Neurod1 and Myod-responsive genes, probably by heterodimerization with class A basic helix-loop-helix factors.
Despite the presence of an intact basic domain, BHLHB5 does not bind to DNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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