Thermo Fisher Scientific CARKL Polyclonal Antibody
Human CARKL 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS(40% 글리세롤) 용액 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장.
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- PA564191
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CARKL. Recombinant protein control fragment (Product #RP-103945). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2639294 |
Product Specific Information
Immunogen sequence:
ILQALHECLA ALPRPQLRSV VGIGVSGQMH GVVFWKTGQG CEWTEGGITP VFEPRAVSHL VTWQDGRCSS EFLASLPQPK SHLSVATGFG CATIFWLLKY R
Highest antigen sequence identity to orthologs:
- Mouse: 80%
- Rat: 79%
Target Information
The protein encoded by this gene has weak homology to several carbohydrate kinases, which are involved in phosphorylation of sugars as they enter a cell, preventing their return across the membrane. Sequence variation suggests possible differences in substrate specificity, cofactors, or kinetic properties compared to known carbohydrate kinases. The gene is located in a region commonly deleted in cystinosis patients, indicating a potential role as a modifier of the cystinosis phenotype. The genomic region also contains numerous Alu repetitive sequences, often associated with chromosomal rearrangements.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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