Thermo Fisher Scientific TIMP1 Monoclonal Antibody (102D1), Biotin

Applications

Tested Dilution

Publications

Western Blot (WB)

1:50

View 6 publications 6 publications

Immunohistochemistry (IHC)

-

View 24 publications 24 publications

Immunohistochemistry (Paraffin) (IHC (P))

1-2 µg/mL

-

ELISA (ELISA)

-

View 1 publication 1 publication

Neutralization (Neu)

-

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Human, Mouse, Rat

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

102D1

Immunogen

Recombinant human TIMP-1

Conjugate

Biotin Biotin Biotin

View additional formats

• Unconjugated
• Request custom conjugation

Form

Liquid

Concentration

0.2 mg/mL

Purification

Protein G

Storage buffer

PBS, pH 7.4, with 0.2% BSA

Contains

0.09% sodium azide

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_11004450

Product Specific Information

MA5-13685 targets TIMP-1 in IHC (P) and WB applications and shows reactivity with Human samples.

The MA5-13685 immunogen is recombinant human TIMP-1.

Target Information

TIMP1 (metalloproteinase inhibitor 1) is a metalloproteinase inhibitor that functions by forms one-to-one complexes with target metallproteinases, such as collagenases, and irreversible inactivates them by binding to their catalytic zinc cofactor. TIMP1 acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP14, and MMP16. It also functions as a growth factor that regulates cell differenation, migration, and cell death. TIMP1 activates cellular signaling cascades via CD63 and ITGB1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.