Thermo Fisher Scientific ErbB2 (HER-2) Monoclonal Antibody (3B5)
HER2/ErbB2 단백질을 표적하는 Mouse IgG1 단클론 항체로, WB, IHC, ICC, Flow, ELISA, IP 등 다양한 응용에 적합. Human, Mouse, Rat 등에서 반응성이 확인됨. 연구용으로만 사용 가능.
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Thermo Fisher Scientific ErbB2 (HER-2) Monoclonal Antibody (3B5)
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | - | 19 |
| Immunohistochemistry (IHC) | 1:1,000–1:2,000 | 30 |
| Immunohistochemistry (Paraffin) (IHC (P)) | - | 1 |
| Immunocytochemistry (ICC/IF) | 1:50–1:500 | 5 |
| Flow Cytometry (Flow) | 1:10–1:100 | - |
| ELISA | - | 4 |
| Immunoprecipitation (IP) | 1:25 | 3 |
Product Specifications
| Specification | Description |
|---|---|
| Published Species | Avian, Cat, Hamster, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3B5 |
| Immunogen | Synthetic peptide from the C-terminus of human c-erbB-2 protein (identical in Rat Neu protein) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10985617 |
Additional Formats
Product Specific Information
MA5-13675 targets HER-2 in IHC, IP, ICC, IF, FACS, and WB applications, showing reactivity with Human, Mouse, Non-human primate, and Rat samples.
The immunogen is a synthetic peptide from the C-terminus of human c-erbB-2 protein, identical to Rat Neu protein.
Target Information
ErbB2 (HER2) is a receptor tyrosine kinase overexpressed in certain breast tumors. Herceptin, used to treat metastatic HER2-positive cancer, is a monoclonal antibody targeting this kinase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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