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Thermo Fisher Scientific HECW1 Polyclonal Antibody
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Thermo Fisher Scientific HECW1 Polyclonal Antibody

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HECW1 단백질을 인식하는 Rabbit Polyclonal Antibody로, 인간 시료에 반응합니다. ICC/IF 실험에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 완충액(40% 글리세롤, 0.02% sodium azide 포함)에서 제공되며, 4°C 또는 -20°C에서 보관합니다.

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마지막 업데이트 2025. 08. 04. 오전 04:17
Thermo Fisher Scientific PA564914 HECW1 Polyclonal Antibody 100 ul pk판매 단위 pk ·
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791,800원VAT 포함 870,980원

Thermo Fisher Scientific · Thermo Fisher Scientific HECW1 Polyclonal Antibody

Applications

Immunocytochemistry (ICC/IF)

  • Tested Dilution: 0.25–2 µg/mL

Product Specifications

항목 내용
Species Reactivity Human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Recombinant Human HECW1. Recombinant protein control fragment (Product # RP-89679)
Conjugate Unconjugated
Form Liquid
Concentration 0.2 mg/mL
Purification Antigen affinity chromatography
Storage Buffer PBS, pH 7.2, with 40% glycerol
Contains 0.02% sodium azide
Storage Conditions Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping Conditions Wet ice
RRID AB_2663811

Product Specific Information

Immunogen sequence:
STEPESAQIQD SPMNNLMESG SGEPRSEAPE SSESWKPEQL GEGSVPDGPG NQSIELSRPA EEAAVITEAG DQGMVSVGPE GAGELLAQVQ KDIQPAPSAE ELAEQLDLGE EASALLLEDG EAPAS

  • Highest antigen sequence identity to the following orthologs:
    • Mouse: 45%
    • Rat: 44%

Target Information

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3, and mutant SOD1 that lead to motor neuron death in FALS.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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