Thermo Fisher Scientific SOAT2 Monoclonal Antibody (OTI2E12), TrueMAB

Applications

Tested Applications and Dilutions

• Immunohistochemistry (Paraffin) [IHC (P)]: 1:150

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

The SOAT2 gene encodes a membrane-bound enzyme located in the endoplasmic reticulum that catalyzes the formation of intracellular cholesterol esters from long-chain fatty acyl CoA and cholesterol. These cholesterol esters are stored as cytoplasmic lipid droplets.
The enzyme is involved in cholesterol absorption in the intestine and in the assembly and secretion of apolipoprotein B-containing lipoproteins such as very low-density lipoprotein (VLDL).
Several alternatively spliced transcript variants have been described, though their full-length forms are not fully characterized.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.