Thermo Fisher Scientific AQP4 Polyclonal Antibody
Thermo Fisher Scientific의 AQP4 Polyclonal Antibody는 마우스 및 랫트 시료에서 AQP4 단백질 검출에 적합한 항체입니다. Western blot 및 IHC(P) 검증 완료. 동결건조 형태로 제공되며, 장기 보관 시 -20°C에서 안정적입니다. 연구용 전용 제품입니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunohistochemistry (Paraffin) (IHC(P)) | 1:1,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from mouse AQP4 conjugated to blue carrier protein was used as the antigen |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
- The peptide is homologous in rat.
- Specificity: AQP4.
Target Information
In skeletal muscle, AQP4 (aquaporin 4, also known as mercurial insensitive water channel) localizes to the sarcolemma of fast-twitch muscle fibers. Aquaporins (AQPs) are a large family of integral membrane water transport channel proteins that facilitate the transport of water through the cell membrane. This function is conserved across animals, plants, and bacteria. Many isoforms of aquaporin have been identified in mammals, designated AQP0 through AQP10. Aquaporins are widely distributed, and it is common for multiple AQP types to coexist in the same cell. Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9, and one of the two AQP10 transcripts are also permeable to urea and glycerol.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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