Thermo Fisher Scientific HTR2B Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:3,000

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human 5-HT2B receptor. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:HTR2B,uniProtId:P41595-1,ncbiNodeId:9606,antigenRange:1,antigenLength:481,antigenImageFileName:PA5-85605_HTR2B_P41595-1_Rabbit.svg,antigenImageFileNamePDP:PA5-85605_HTR2B_P41595-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2.29 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2792745

Product Specific Information

Keep as concentrated solution.

Positive Control: SH-SY5Y, SH-SY5Y membrane fraction extract, unboiled SH-SY5Y, unboiled SH-SY5Y membrane fraction extract, mouse liver.

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

HTR2B is a g-protein coupled receptor for 5-hydroxytryptamine (serotonin). It functions as a receptor for various ergot alkaloid derivatives and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. HTR2B also plays a role in perception of pain, regulation of behavior. It is required to normal proliferation of embryonic cardiac myocytes and normal heart development.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.