Thermo Fisher Scientific HTR2B Polyclonal Antibody
Rabbit polyclonal antibody targeting human 5-HT2B receptor (HTR2B). Validated for Western blot (1:500–1:3,000). Supplied as liquid, 2.29 mg/mL. Suitable for research use in SH-SY5Y and mouse liver samples. Store at 4°C short term or -20°C long term.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
- Publications: Refer to Thermo Fisher database for references.
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human 5-HT2B receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.29 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792745 |
Product Specific Information
- Keep as concentrated solution.
- Positive Control: SH-SY5Y, SH-SY5Y membrane fraction extract, unboiled SH-SY5Y, unboiled SH-SY5Y membrane fraction extract, mouse liver.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
HTR2B is a G-protein coupled receptor for 5-hydroxytryptamine (serotonin). It functions as a receptor for various ergot alkaloid derivatives and psychoactive substances. Ligand binding causes a conformational change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. HTR2B also plays a role in pain perception and behavioral regulation. It is required for normal proliferation of embryonic cardiac myocytes and proper heart development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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