Thermo Fisher Scientific TTLL12 Polyclonal Antibody
Human TTLL12 단백질을 타겟으로 하는 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS buffer와 glycerol 포함. 암 연구 및 세포 단백질 발현 분석에 적합.
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Thermo Fisher Scientific TTLL12 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TTLL12. Recombinant protein control fragment (Product #RP-91500). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2649095 |
Product Specific Information
Immunogen sequence:
DYEKHFTVMN YDPDVVLKQV HCEEFIPEFE KQYPEFPWTD VQAEIFRAFT ELFQVACAKP PPLGLCDYPS SRAMYAVDLM LKWDNGPDGR RVMQPQILEV NFNPDCERAC RYHPTFFNDV FSTLFLDQPG
Highest antigen sequence identity to the following orthologs:
- Mouse: 89%
- Rat: 85%
Target Information
TTLL12 (tubulin tyrosine ligase-like family, member 12) is a 644 amino acid protein that contains one TTL domain. Among the fourteen members of the TTLL family that modify tubulin, TTLL12 is the least characterized. It is highly expressed in metastatic prostate cancer cell lines and is considered a potential target for tumor therapy. Overexpression of TTLL12 may alter chromosome ploidy, while downregulation influences post-translational modifications of tubulin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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