Thermo Fisher Scientific SPHK1 Polyclonal Antibody
상품 옵션 정보 | |||||||||
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 재고 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
BS-2652R | - | Thermo Fisher Scientific BS-2652R SPHK1 Polyclonal Antibody 100 ul pk | 재고문의 | pk | 564,000원 | - | 620,400원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
Western Blot (WB)
1:30
Immunohistochemistry (Paraffin) (IHC (P))
Assay-dependent
Immunohistochemistry (Frozen) (IHC (F))
1:100-1:500
Immunocytochemistry (ICC/IF)
1:50-1:200
Flow Cytometry (Flow)
1:20-100
ELISA (ELISA)
1:500-1:1,000
Product Specifications
Species Reactivity
Human, Mouse, Rat
Host/Isotype
Rabbit / IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human SPHK1, amino acids 1-100. if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
SPHK1,
uniProtId:
Q9NYA1-1,
ncbiNodeId:
9606,
antigenRange:
1-100,
antigenLength:
384,
antigenImageFileName:
BS-2652R_SPHK1_Q9NYA1-1_Rabbit.svg,
antigenImageFileNamePDP:
BS-2652R_SPHK1_Q9NYA1-1_Rabbit_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
SPHK1, along with SPHK2, catalyzes the phosphorylation of sphingosine producing the signaling molecule sphingosine-1-phosphate (S1P). S1P signals through G-protein coupled receptors and controls diverse cellular processes. Inhibitors of SPHKs are viewed as potential therapeutics for the treatment of cancer. SPHK1 catalyzes the phosphorylation of sphingosine to sphingosine 1 phosphate (S1P), an important signaling molecule with intra- and extracellular functions. Inside the cell S1P acts as a signaling molecule like other sphingolipid metabolites like ceramide and sphingosine. S1P has been implicated in regulating cell differentiation, calcium mobilization from intracellular stores, and apoptosis. The cell surface receptors for S1P are the EDG family of G protein-coupled receptors (S1P Receptors).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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