
Thermo Fisher Scientific Lactyl-Histone H3 (Lys14) Polyclonal Antibody
Rabbit polyclonal antibody specific for lactylated Histone H3 (Lys14). Validated for WB and ELISA in human, mouse, and rat samples. Affinity purified, liquid form, ideal for chromatin structure and histone modification research.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Concentration: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic lactylated peptide around K14 of human Histone H3 (NP_0035201) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.63 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901527 |
Product Specific Information
- Positive Samples: MCF7, NIH/3T3, C6
- Immunogen sequence: TGGKA
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fibers in eukaryotes. Approximately 146 bp of DNA wraps around a nucleosome, an octamer composed of pairs of core histones (H2A, H2B, H3, and H4). Chromatin fibers are further compacted via interactions between linker histone H1 and DNA between nucleosomes.
This gene, part of the histone H3 family, is intronless and replication-dependent. Transcripts lack polyA tails and instead contain a palindromic termination element. It is located in the large histone gene cluster on chromosome 6p22–p21.3.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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