Thermo Fisher Scientific CDC2 p34 Polyclonal Antibody
CDC2 p34 단백항체는 인간, 마우스, 랫트 시료에서 34 kDa cdc2 단백질을 특이적으로 인식하는 폴리클로날 항체입니다. WB, IHC, ELISA, IP 등 다양한 응용에 사용 가능하며, KLH 결합 CDC2 펩타이드로 면역생성되었습니다. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific CDC2 p34 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:250–1:5,000 |
| Immunohistochemistry (IHC) | 1:200–1:1,000 |
| ELISA | 1:60,000 |
| Immunoprecipitation (IP) | 1:250–1:5,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CDC2 peptide corresponding to the C-terminus of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 85 mg/mL |
| Storage Buffer | Whole serum |
| Contains | 0.01% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Store vial at -20°C prior to opening.
- Aliquot contents and freeze at -20°C or below for extended storage.
- Avoid cycles of freezing and thawing.
- Centrifuge product if not completely clear after standing at room temperature.
- Stable for several weeks at 4°C as an undiluted liquid.
- Dilute only prior to immediate use.
Antiserum specifically reacts with a 34 kDa cdc2 protein from human, rat, and mouse tissue. No reaction observed against other related cyclin-dependent kinases. Cross-reactivity with cdc2 from other species may also occur.
Target Information
CDK1 (Cell Division Control protein 1) is essential for the completion of START, the controlling event in the cell cycle required to initiate mitosis.
CDK1 acts as a catalytic subunit of the M-Phase Promoting Factor (MPF), which induces entry into mitosis and is conserved across eukaryotes.
Phosphorylation of Bcl-2 in G2/M phase-arrested cells following photodynamic therapy with hypericin involves a CDK1-mediated signal that delays apoptosis onset.
Therapeutic potential of CDK inhibitor NU2058 in androgen-independent prostate cancer has been demonstrated.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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