Thermo Fisher Scientific CETP Polyclonal Antibody
Thermo Fisher Scientific의 CETP Polyclonal Antibody는 인간 CETP 단백질을 표적으로 하는 토끼 IgG 항체로서 WB, IHC, ELISA에 적합합니다. 고순도 친화 크로마토그래피 정제, 액상 형태, 안정적 저장 조건을 제공합니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 300–493 of human CETP (NP_0000692) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.07 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805475 |
Product Specific Information
- Immunogen sequence:
LMLSLMGDEF KAVLETWGFN TNQEIFQEVV GGFPSQAQVT VHCLKMPKIS CQNKGVVVNS SVMVKFLFPR PDQQHSVAYT FEEDIVTTVQ ASYSKKKLFL SLLDFQITPK TVSNLTESSS ESVQSFLQSM ITAVGIPEVM SRLEVVFTAL MNSKGVSLFD IINPEIITRD GFLLLQMDFG FPEHLLVDFL QSLS - Positive Samples: A-549, HepG2, A375, Mouse liver, Rat liver
- Cellular Location: Extracellular space
Target Information
High density lipoproteins (HDLs) function jointly with lecithin:cholesterol acyltransferase and CETP to facilitate cholesterol transport from tissues to the liver. This reverse cholesterol transport mechanism is physiologically important for maintaining systemic cholesterol levels. CETP mediates neutral lipid transfer activity in plasma across numerous species and accelerates the exchange of lipid components between pro- and anti-atherogenic lipoprotein fractions. Elevated CETP levels have been associated with increased risk of coronary heart disease, making CETP a potential target for atherosclerosis prevention.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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