Thermo Fisher Scientific PMEPA1/TMEPAI (Tumor Suppressor Oncoprotein) Monoclonal Antibody (rPMEPA1/6422)
PMEPA1/TMEPAI 종양 억제 단백질을 표적하는 Thermo Fisher Scientific의 단클론 항체. 인간 시료 반응성, IHC(P) 및 IHC(PFA) 적용 가능. 단클론 Mouse IgG1 형식, Protein A/G 정제, 액상 형태로 4°C 보관.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | rPMEPA1/6422 |
| Immunogen | Recombinant full-length human PMEPA1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a transmembrane protein containing a Smad interacting motif (SIM). Expression is induced by androgens and transforming growth factor beta (TGF-β). The encoded protein suppresses androgen receptor and TGF-β signaling pathways through interactions with Smad proteins. Overexpression may contribute to various cancers. Multiple alternatively spliced transcript variants are known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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