Thermo Fisher Scientific CD105 Polyclonal Antibody
Rabbit polyclonal antibody targeting human CD105 (Endoglin), validated for WB and IP applications. High specificity and affinity purified via antigen chromatography. Supplied in PBS without preservative, suitable for endothelial and tumor vascular rese...
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- PA5117933
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunoprecipitation (IP)
- Tested Dilution: 1–5 µL/mg of lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the C-terminus of Human Endoglin (CD105/ENG) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography, Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2902539 |
Target Information
CD105 (Endoglin) is a Type I transmembrane protein highly expressed on human vascular endothelial cells. It forms an O- and N-glycosylated homodimer. Upregulation of endoglin expression is observed in tumor vasculature and proliferating cells, indicating its role as a proliferation-associated endothelial marker. CD105 binds TGF-β1 and TGF-β3 with high affinity but not TGF-β2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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