Thermo Fisher Scientific TRPM2 Polyclonal Antibody
TRPM2 단백질을 인식하는 Thermo Fisher Scientific의 sheep 유래 polyclonal antibody. Western blot 및 IHC에 사용 가능. 인간 종에 반응하며, lyophilized 형태로 제공. 연구용으로 산화 스트레스 관련 세포사멸 연구에 적합.
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- OST00030W-100UL
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Thermo Fisher Scientific TRPM2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Sheep / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the 4th cytoplasmic domain of human TRPM2 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: TRPM2.
Target Information
TRPM2 belongs to the ion transport protein family, including Sodium, Potassium, and Calcium ion channels.
This family is characterized by proteins possessing six transmembrane helices, with the last two helices flanking a loop determining ion selectivity.
TRPM2 is activated by oxidative stress and confers susceptibility to cell death.
It is a calcium-permeable cation channel regulated by free intracellular ADP-ribose.
Several alternatively spliced transcript variants of the TRPM2 gene have been described, but their full-length nature is not known.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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