Thermo Fisher Scientific Hepcidin 25 Polyclonal Antibody
Hepcidin 25 폴리클로날 항체로 마우스와 랫트 시료에 반응합니다. IHC(P) 등 다양한 면역분석에 사용 가능합니다. KLH 결합 합성 펩타이드(aa 60-84)로부터 유래되었으며, Protein A로 정제된 액상 항체입니다. 철 항상성 연구용으로 적합합니다.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from rat Hepcidin, amino acids 60–84 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The product encoded by this gene is involved in the maintenance of iron homeostasis and is necessary for the regulation of iron storage in macrophages and intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22, and 25 amino acids. These active peptides are rich in cysteines forming intramolecular bonds that stabilize their beta-sheet structures and exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B (juvenile hemochromatosis), leading to severe iron overload, cardiomyopathy, cirrhosis, and endocrine failure.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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