Thermo Fisher Scientific GPCR TGR5/GPBAR1 Polyclonal Antibody
Human GPBAR1(TGR5) 인식 Rabbit Polyclonal Antibody로, Western Blot 및 IHC(P) 실험에 적합. KLH 결합 합성 펩타이드로 면역화되었으며, Protein A 정제 및 액상 형태로 제공. 에너지 항상성 및 담즙산 신호전달 연구에 활용 가능.
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Applications
- Western Blot (WB): Assay-dependent
- Immunohistochemistry (Paraffin) (IHC (P)): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human GPBAR1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. It functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces intracellular cAMP production, activation of MAP kinase signaling, and receptor internalization. The receptor is involved in suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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배송/결제/교환/반품 안내
배송 정보
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