Thermo Fisher Scientific CD162 Recombinant Rabbit Monoclonal Antibody (108)
인간 PSGL-1/CD162/SELPLG 단백질을 인식하는 재조합 토끼 단일클론 항체. Western blot, ELISA, Immunoprecipitation에 사용 가능. 고특이성, 로트 간 일관성, 동물 유래 성분 없음. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | View 1 publication |
| ELISA | 1:25,000–1:50,000 | - |
| Immunoprecipitation (IP) | 0.2–1 µL/mg of lysate | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 108 |
| Immunogen | Recombinant Human PSGL-1/CD162/SELPLG Protein (Met1–Gly295) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2785401 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems clone specific antibody DNA sequences from immunoreactive rabbits, followed by screening to select optimal clones for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Superior specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to larger rabbit immune repertoire
This antibody specifically recognizes Human PSGL-1/CD162/SELPLG.
Target Information
CD162 (PSGL-1) is a 120 kDa homodimeric protein expressed on leukocytes and platelets. It binds CD62P (P-selectin), CD62L (L-selectin), and to a lesser extent CD62E (E-selectin). These interactions are crucial for leukocyte adhesion, rolling, and extravasation. CD162 is also an important immune marker of T cell exhaustion in chronic viral infections and cancer.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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