
Thermo Fisher Scientific GABA (B)R2 Polyclonal Antibody
Rabbit polyclonal antibody targeting GABABR2 subunit for human samples. Suitable for Western blot applications with high specificity. Protein A purified, liquid form, unconjugated. Stored at -20°C in PBS buffer with sodium azide preservative.
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Applications
Western Blot (WB)
- Tested Dilution: 1:250–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to aa 42–54 (TRGAPRPPPSSPP) of the rat GABABR2 subunit |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The multi-pass membrane protein GABBR2 belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily.
GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate neurotransmitter release, ion channel activity, and adenylyl cyclase function.
This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is functional alone.
Allelic variants of this gene have been associated with nicotine dependence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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