Thermo Fisher Scientific FLAP Polyclonal Antibody
FLAP 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P) 검증 완료. Human ALOX5AP 단백질에 특이적이며, 항원 친화 크로마토그래피로 정제됨. PBS/glycerol buffer에 보관되며 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ALOX5AP. Recombinant protein control fragment (Product # RP-89567) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2790082 |
Product Specific Information
Immunogen sequence:
HKVEHESRTQ NGRSFQRTGT LAFERVYTAN QNCVDAYPTF LAVL
Target Information
ALOX5AP is a protein which, together with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites involved in inflammatory responses such as asthma, arthritis, and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit its activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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