Thermo Fisher Scientific CRMP3 Recombinant Rabbit Monoclonal Antibody (8N2S10)
Recombinant rabbit monoclonal antibody targeting CRMP3/DPYSL4. Validated for WB and ELISA with high specificity to rat CRMP3. Suitable for neural signal transduction studies. Provided in liquid form with affinity-purified quality and stable storage buf...
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:5,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 8N2S10 |
| Immunogen | A synthetic peptide corresponding to amino acids 1–100 of human CRMP3/DPYSL4 (O14531) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.33 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911755 |
Product Specific Information
- Positive test controls include: C6
- Immunogen sequence:
MSFQGKKSIP RITSDRLLIR GGRIVNDDQS FYADVHVEDG LIKQIGENLI VPGGIKTIDA HGLMVLPGGV DVHTRLQMPV LGMTPADDFC QGTKAALAGG
Target Information
Collapsin response mediator proteins (CRMPs), including CRMP-1 (DRP-1), CRMP-2 (DRP-2 or TOAD64), CRMP-3 (DRP-4), CRMP-4 (DRP-3) and CRMP-5 (DRP-5), mediate signal transduction after exposure of neural cells to the axon guidance molecule Semaphorin 3A (SEMA3A)/collapsin.
CRMPs are expressed in the developing cerebral cortex and neocortical neurons and are responsive to SEMA3A. In the adult brain, CRMP expression is downregulated but remains active in regions with differentiation and plasticity potential.
CRMP-3 is transiently expressed in developing spinal cord and selectively in the postnatal cerebellum.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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