Thermo Fisher Scientific PSMC3IP Polyclonal Antibody
PSMC3IP 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. 인간 시료에 반응하며 Western blot에 적합. 단백질 A로 정제된 액상 항체로, PBS와 2% sucrose 용액에 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1.25 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human PSMC3IP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2576818 |
Product Specific Information
Peptide sequence:
RLKNIKAATN HVTPEEKEQV YRERQKYCKE WRKRKRMATE LSDAILEGYP
Sequence homology:
Cow: 93%
Dog: 100%
Goat: 86%
Guinea Pig: 93%
Horse: 100%
Human: 100%
Mouse: 86%
Rabbit: 86%
Rat: 93%
Target Information
PSMC3IP plays an important role in meiotic recombination. It stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis.
The PSMC3IP/MND1 complex binds DNA, stimulates recombinase activity of DMC1, and promotes D-loop formation from double-strand DNA.
This complex stabilizes presynaptic RAD51 and DMC1 filaments on single-strand DNA to capture double-strand DNA, facilitating homologous pairing.
It may also inhibit HIV-1 TAT activity and modulate proteasome activity through association with PSMC3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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