Thermo Fisher Scientific SH3BP2 Polyclonal Antibody
SH3BP2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot과 IHC(Paraffin)에서 검증됨. 인체 시료 반응성, 친화 크로마토그래피로 정제, PBS/glycerol buffer 보존. 연구용으로만 사용 가능.
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- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SH3BP2 (Accession P78314), corresponding to amino acid residues P393–D443 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850189 |
Product Specific Information
Antibody detects endogenous levels of total SH3BP2.
Target Information
The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain.
It binds to SH3 domains of several proteins including ABL1 and SYK tyrosine kinases, functioning as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, NK, and basophilic cells.
Mutations in this gene cause cherubism. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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