Thermo Fisher Scientific CD4 Monoclonal Antibody (S3.5), PE-Texas Red
인간 CD4 항원을 인식하는 mouse IgG2a 단클론 항체로, PE-Texas Red로 표지되어 있습니다. Flow cytometry 및 immunocytochemistry에 적합하며, 488 nm 레이저로 다중 형광 검출이 가능합니다. 4°C 암소 보관, PBS/sucrose/BSA buffer 포함.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunocytochemistry (ICC/IF) | - | View 2 publications |
| Flow Cytometry (Flow) | Assay-Dependent | View 19 publications |
| Miscellaneous PubMed (Misc) | - | View 6 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | S3.5 |
| Immunogen | Human CD4 |
| Conjugate | PE-Texas Red |
| Excitation / Emission Max | 567 / 615 nm |
| Form | Liquid |
| Purification | Purified |
| Storage Buffer | PBS with 10% sucrose, BSA |
| Contains | 0.1% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10371766 |
Additional Formats Available
- Unconjugated
- Alexa Fluor 405
- Alexa Fluor 488
- Alexa Fluor 700
- APC
- APC-Alexa Fluor 750
- APC-Cyanine5.5
- FITC
- Pacific Blue
- Pacific Orange
- PE
- PE-Alexa Fluor 610
- PE-Alexa Fluor 700
- PE-Cyanine5.5
- PE-Cyanine7
- PerCP
- Qdot 605
- Qdot 655
- Qdot 705
- Qdot 800
- TRI-COLOR
- Request custom conjugation
Product Specific Information
The R-phycoerythrin (PE)-Texas Red conjugate permits simultaneous multicolor labeling and detection of multiple targets using a single excitation source—the 488 nm line of the argon-ion laser.
Target Information
The CD4 antigen is involved in the recognition of MHC class II molecules and acts as a co-receptor for HIV. CD4 is primarily expressed in T helper cells but can also be found in monocytes, macrophages, and dendritic cells. Tissue-level expression includes thymus, lymph nodes, tonsils, spleen, and certain regions of the brain and gut. CD4 contributes to early T-cell activation via association with the T-cell receptor complex and protein tyrosine kinase Lck. It may also mediate neuronal damage in immune-related CNS diseases. Multiple alternatively spliced transcripts have been identified (RefSeq, July 2017).
Analyte Specific Reagent
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