Thermo Fisher Scientific CD4 Monoclonal Antibody (S3.5), FITC
인간 CD4 항원에 특이적인 마우스 단클론 항체로 FITC 형광 표지되어 있습니다. Flow Cytometry에 적합하며 높은 형광 효율과 수용성이 우수합니다. PBS/BSA 버퍼에 보관하며 4°C 암소 저장이 권장됩니다.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: Assay-Dependent
- Publications: View 12 publications
Miscellaneous PubMed (Misc)
- Publications: View 4 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | S3.5 |
| Immunogen | Human CD4 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Purification | Purified |
| Storage Buffer | PBS with 4 mg/mL BSA |
| Contains | 0.1% Sodium Azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10392546 |
Additional Formats Available
- Unconjugated
- Alexa Fluor 405
- Alexa Fluor 488
- Alexa Fluor 700
- APC
- APC-Alexa Fluor 750
- APC-Cyanine5.5
- Pacific Blue
- Pacific Orange
- PE
- PE-Alexa Fluor 610
- PE-Alexa Fluor 700
- PE-Cyanine5.5
- PE-Cyanine7
- PE-Texas Red
- PerCP
- Qdot 605
- Qdot 655
- Qdot 705
- Qdot 800
- TRI-COLOR
- Request custom conjugation
Product Specific Information
FITC conjugates provide relatively high absorptivity, excellent fluorescence quantum yield, and good water solubility, making them suitable for various fluorescence-based assays.
Target Information
CD4 antigen is involved in the recognition of MHC class II molecules and acts as a co-receptor for HIV. It is primarily expressed on T-helper lymphocytes but can also be found on monocytes, macrophages, and dendritic cells.
At the tissue level, CD4 expression is observed in thymus, lymph nodes, tonsils, spleen, and certain regions of the brain and gut.
CD4 contributes to T-cell activation through association with the T-cell receptor complex and protein tyrosine kinase Lck. It may also mediate neuronal damage in immune-related diseases of the CNS.
Multiple alternatively spliced transcripts have been identified (RefSeq, July 2017).
Classification
Analyte Specific Reagent
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