Thermo Fisher Scientific CD4 Monoclonal Antibody (S3.5), FITC

Applications

Flow Cytometry (Flow)

• Tested Dilution: Assay-Dependent
• Publications: View 12 publications

Miscellaneous PubMed (Misc)

• Publications: View 4 publications

Product Specifications

Additional Formats Available

• Unconjugated
• Alexa Fluor 405
• Alexa Fluor 488
• Alexa Fluor 700
• APC
• APC-Alexa Fluor 750
• APC-Cyanine5.5
• Pacific Blue
• Pacific Orange
• PE
• PE-Alexa Fluor 610
• PE-Alexa Fluor 700
• PE-Cyanine5.5
• PE-Cyanine7
• PE-Texas Red
• PerCP
• Qdot 605
• Qdot 655
• Qdot 705
• Qdot 800
• TRI-COLOR
• Request custom conjugation

Product Specific Information

FITC conjugates provide relatively high absorptivity, excellent fluorescence quantum yield, and good water solubility, making them suitable for various fluorescence-based assays.

Target Information

CD4 antigen is involved in the recognition of MHC class II molecules and acts as a co-receptor for HIV. It is primarily expressed on T-helper lymphocytes but can also be found on monocytes, macrophages, and dendritic cells.
At the tissue level, CD4 expression is observed in thymus, lymph nodes, tonsils, spleen, and certain regions of the brain and gut.
CD4 contributes to T-cell activation through association with the T-cell receptor complex and protein tyrosine kinase Lck. It may also mediate neuronal damage in immune-related diseases of the CNS.
Multiple alternatively spliced transcripts have been identified (RefSeq, July 2017).

Classification

Analyte Specific Reagent

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