Thermo Fisher Scientific TOB2 Polyclonal Antibody
Rabbit polyclonal antibody targeting human TOB2 protein. Validated for ICC/IF applications with high specificity. Supplied as liquid form, unconjugated, purified by antigen affinity chromatography. Suitable for research use in cell cycle and transcript...
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human TOB2. Recombinant protein control fragment (Product #RP-105739) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C and avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2663277 |
Product Specific Information
Immunogen sequence:
PELDKEIKSSF NPDAQVFVPI GSQDSSLSNS PSPSFGQSPS PTFIPRSAQP ITFTTASFAA TKFGSTKMKK GGGAASGGGV ASSGAGGQQP PQQPRMARSP TNSLLKHKSL SLSMHSLNFI TANPAPQSQL SPNAKEFVYN GGGSPSLFFD AADGQGSGTP GPFGGSGAGT CNSS
- Highest antigen sequence identity to orthologs: mouse 86%, rat 88%
Target Information
TOB2 is a 344-amino-acid protein belonging to the Tob/BTG1 anti-proliferative family, characterized by BTG/Tob homology domains. It inhibits cell cycle progression from G0/G1 to S phase and interacts with Caf1, a CCR4 complex component. TOB2 plays roles in spermatogenesis, embryonic patterning, osteogenesis, T-cell activation, learning, and memory. It functions mainly as a transcriptional repressor and is ubiquitously expressed in most tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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