Thermo Fisher Scientific GEF-H1 Polyclonal Antibody
GEF-H1 단백질을 인식하는 Thermo Fisher Scientific의 Sheep Polyclonal Antibody. Western blot, ICC/IF, IP 등 다양한 응용 가능. 1 mg/mL 농도의 액상 형태로 제공되며 PBS buffer에 sodium azide 함유. 연구용으로만 사용 가능.
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- PA112491
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
Immunocytochemistry (ICC/IF)
- Tested Dilution: Assay-dependent
Immunoprecipitation (IP)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Protein corresponding to residues 2–447 of the Lfc protein fused to GST |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS |
| Contains | 0.08% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2289953 |
Target Information
GEF-H1 activates Rho GTPases by promoting the exchange of GDP and GTP.
Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli via G protein-coupled receptors.
GEF-H1 may be involved in epithelial barrier permeability, cell motility and polarization, dendritic spine morphology, antigen presentation, leukemic cell differentiation, cell cycle regulation, innate immune response, and cancer.
Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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