Thermo Fisher Scientific SH3PXD2A Polyclonal Antibody
SH3PXD2A 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간 및 생쥐 시료에 반응하며 WB, ICC/IF, ELISA에 적합. 액상 형태로 5.14 mg/mL 농도, PBS/glycerol buffer에 보관. 연구용으로만 사용 가능.
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Thermo Fisher Scientific SH3PXD2A Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 806–1105 of human SH3PXD2A (NP_0554462) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 5.14 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901786 |
Product Specific Information
- Positive Samples: HeLa
- Immunogen Sequence:
TKKEWEGPAT SYMTCSAYQK VQDSEISFPA GVEVQVLEKQ ESGWWYVRFG ELEGWAPSHY LVLDENEQPD PSGKELDTVP AKGRQNEGKS DSLEKIERRV QALNTVNQSK KATPPIPSKP PGGFGKTSGT PAVKMRNGVR QVAVRPQSVF VSPPPKDNNL SCALRRNESL TATDGLRGVR RNSSFSTARS AAAEAKGRLA ERAASQGSDS PLLPAQRNSI PVSPVRPKPI EKSQFIHNNL KDVYVSIADY EGDEETAGFQ EGVSMEVLER NPNGWWYCQI LDGVKPFKGW VPSNYLEKKN
Target Information
Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation, and invasiveness of certain cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs), and phosphoinositides. Acts as an organizer protein enabling NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and localization. In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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