Thermo Fisher Scientific SH3PXD2A Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 806-1105 of human SH3PXD2A (NP_0554462) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SH3PXD2A,uniProtId:Q5TCZ1-1,ncbiNodeId:9606,antigenRange:806-1105,antigenLength:1133,antigenImageFileName:PA5-117156_SH3PXD2A_Q5TCZ1-1_Rabbit.svg,antigenImageFileNamePDP:PA5-117156_SH3PXD2A_Q5TCZ1-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

5.14 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2901786

Product Specific Information

Positive Samples: HeLa

Immunogen sequence: TKKEWEGPAT SYMTCSAYQK VQDSEISFPA GVEVQVLEKQ ESGWWYVRFG ELEGWAPSHY LVLDENEQPD PSGKELDTVP AKGRQNEGKS DSLEKIERRV QALNTVNQSK KATPPIPSKP PGGFGKTSGT PAVKMRNGVR QVAVRPQSVF VSPPPKDNNL SCALRRNESL TATDGLRGVR RNSSFSTARS AAAEAKGRLA ERAASQGSDS PLLPAQRNSI PVSPVRPKPI EKSQFIHNNL KDVYVSIADY EGDEETAGFQ EGVSMEVLER NPNGWWYCQI LDGVKPFKGW VPSNYLEKKN

Target Information

Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.