Thermo Fisher Scientific mGluR4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

5-15 µg/mL

-

Flow Cytometry (Flow)

2.5 µg/1x10^6 cells

-

Product Specifications

Host/Isotype

Sheep / IgG

Class

Polyclonal

Type

Antibody

Immunogen

CHO-derived recombinant human mGluR4 Lys33-Ser518

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.2 mg/mL

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2607818

Product Specific Information

In direct ELISAs, approximately 40% cross-reactivity with recombinant human (rh) mGluR7 and rhmGluR8 is observed, and less than 8% cross-reactivity with rhmGluR3 is observed.

Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.

Target Information

The Metabotropic Glutamate Receptor mGluR4/GRM4 binds L-glutamate, the major excitatory neurotransmitter in the central nervous system, which activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.