Thermo Fisher Scientific mGluR4 Polyclonal Antibody
Thermo Fisher Scientific의 mGluR4 Polyclonal Antibody는 인간 mGluR4 단백질을 인식하는 양에서 유래한 IgG 항체입니다. 면역조직화학(IHC) 및 유세포분석(Flow Cytometry)에 적합하며, 동결건조 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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- PA547923
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 5–15 µg/mL
Flow Cytometry (Flow)
- Tested Dilution: 2.5 µg / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CHO-derived recombinant human mGluR4 Lys33–Ser518 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2607818 |
Product Specific Information
- In direct ELISAs, approximately 40% cross-reactivity with recombinant human mGluR7 and mGluR8 is observed.
- Less than 8% cross-reactivity with recombinant human mGluR3 is observed.
- Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.
Target Information
The Metabotropic Glutamate Receptor mGluR4 (GRM4) binds L-glutamate, the major excitatory neurotransmitter in the central nervous system. This receptor activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions.
Metabotropic glutamate receptors are a family of G protein-coupled receptors, divided into three groups based on sequence homology, signal transduction mechanisms, and pharmacologic properties.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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