Thermo Fisher Scientific CD158b Monoclonal Antibody (DX27)
인간 CD158b 단백질을 인식하는 Mouse IgG1 단클론 항체. IHC(P) 및 유세포분석(Flow Cytometry)에 적합. 단백질 A로 정제된 액상 형태로 제공되며, 0.5 mg/mL 농도. 단기 4°C, 장기 -20°C 보관 권장.
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- 605-010
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- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 2–10 µg/mL
Flow Cytometry (Flow)
- Tested Dilution: 0.5–5 µg/10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | DX27 |
| Immunogen | Recombinant protein of human CD158b |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive Control: Tonsil
- Cellular Location: Membrane, cytoplasm
Target Information
NKAT (NK-associated transcripts) gene products, also known as killer immunoglobulin-like receptors (KIRs), downregulate NK cell cytotoxicity upon recognition of specific class I MHC molecules on target cells.
These receptors are characterized by two to three immunoglobulin-superfamily domains and a cytoplasmic domain containing an antigen receptor activation motif (ARAM).
KIRs and other inhibitory receptors share a cytoplasmic sequence (I/VxYxxL/V) known as ITIM (immunoreceptor tyrosine-based inhibitory motif).
Human inhibitory receptor KIR2DL3 (CD158b) specifically recognizes the human MHC class I molecule HLA-Cw3 and related alleles.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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