Thermo Fisher Scientific HTRA3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Human HTRA3. Recombinant protein control fragment (Product #RP-107289). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:HTRA3,uniProtId:P83110-1,ncbiNodeId:9606,antigenRange:189-242,antigenLength:453,antigenImageFileName:PA5-66637_HTRA3_P83110-1_Rabbit.svg,antigenImageFileNamePDP:PA5-66637_HTRA3_P83110-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2663094

Product Specific Information

Immunogen sequence: NAHVVSSNSAA PGRQQLKVQL QNGDSYEATI KDIDKKSDIA TIKIHPKKKL PVL

Highest antigen sequence identity to the following orthologs - mouse 89%, rat 85%.

Target Information

HtrA3 belongs to the human high-temperature requirement factor A (HtrA) family. It is also called pregnancy-related serine protease. HtrA3 has two isoforms (long and short), which is produced by alternative splicing. Similar to HtrA1, HtrA3 binds to various TGF-beta proteins and inhibited the signaling of BMP-4, -2 and TGF-beta 1. HtrA3 does not inhibit signaling originated from a constitutively active BMP receptor, indicating that the inhibition occurred upstream of the cell surface receptor.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.