Thermo Fisher Scientific HTRA3 Polyclonal Antibody
HTRA3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간 시료 반응성, ICC/IF에 적합하며 항원 친화 크로마토그래피로 정제됨. PBS 기반 저장용액 포함, 연구용으로만 사용 가능.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human HTRA3. Recombinant protein control fragment (Product #RP-107289) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2663094 |
Product Specific Information
Immunogen sequence:
NAHVVSSNSAA PGRQQLKVQL QNGDSYEATI KDIDKKSDIA TIKIHPKKKL PVL
Highest antigen sequence identity to orthologs:
- Mouse: 89%
- Rat: 85%
Target Information
HtrA3 belongs to the human high-temperature requirement factor A (HtrA) family, also known as pregnancy-related serine protease. It has two isoforms (long and short) produced by alternative splicing. Similar to HtrA1, HtrA3 binds to various TGF-beta proteins and inhibits the signaling of BMP-4, BMP-2, and TGF-beta 1. HtrA3 does not inhibit signaling from a constitutively active BMP receptor, indicating inhibition occurs upstream of the cell surface receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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