Thermo Fisher Scientific ARL15 Polyclonal Antibody
ARL15 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot 및 Immunocytochemistry에 적합. 인간 시료에 반응하며 항원 친화 크로마토그래피로 정제됨. PBS/glycerol buffer에 보관, 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human ARL15. Recombinant protein control fragment (Product # RP-105289) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2664971 |
Product Specific Information
Immunogen sequence:
LHSALQHPQLC TLPFLILANH QDKPAARSVQ EIKKYFELEP LARGKRWILQ PCSLDDMDAL KDSFSQLINL LEEKDHEAVR M
Highest antigen sequence identity to the following orthologs:
- Mouse: 98%
- Rat: 98%
Target Information
ADP-ribosylation factors (ARFs) are highly conserved guanine nucleotide binding proteins that enhance the ADP-ribosyltransferase activity of cholera toxin. ARFs are important in eukaryotic vesicular trafficking pathways and play an essential role in the activation of phospholipase D (PC-PLD).
ARL15 (ADP-ribosylation factor-like 15) is a member of the ARF family within the Ras superfamily of small GTPases, involved in multiple regulatory pathways altered in human carcinogenesis. Other related proteins include:
- ARL11: Potential tumor suppressor, may regulate apoptosis
- ARL2: Involved in microtubule dynamics and cell cycle progression
- ARL4: May play a role in neurogenesis during embryonic development
The human ARL15 gene maps to chromosome 5p15, and at least three isoforms are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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