Thermo Fisher Scientific Kir7.1 (extracellular) Polyclonal Antibody, Atto 488

Thermo Fisher Scientific Kir7.1 (extracellular) Polyclonal Antibody, Atto 488

Applications

• Immunohistochemistry (Paraffin) (IHC (P)): Tested dilution 1:50

Species Reactivity

Human, Mouse, Rat

Host / Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

(C)EMNGDLEIDHDVPPE, corresponding to amino acid residues 80–94 of rat KCNJ13, extracellular loop (Kir7.1)

Conjugate

Atto™ 488

Excitation / Emission Max

501 / 523 nm

Form

Lyophilized

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage Buffer

PBS, pH 7.4, with 1% BSA

Contains

0.05% sodium azide

Storage Conditions

• Store at −20 °C
• Avoid freeze/thaw cycles

Shipping Conditions

• Ambient (domestic)
• Wet ice (international)

Product Specific Information

Reconstitution: Add 50 µL double distilled water (DDW), depending on sample size.
The antibody ships lyophilized at room temperature. Upon arrival, store at −20 °C.
Reconstituted solution can be stored at 4 °C for up to 1 week. For longer storage, aliquot and keep at −20 °C.
Avoid multiple freeze/thaw cycles.
Centrifuge all antibody preparations before use (10,000 × g, 5 min).

Target Information

Inward rectifier potassium channels preferentially allow potassium influx rather than efflux.
Their voltage dependence is regulated by extracellular potassium concentration; higher external potassium shifts channel opening to more positive voltages.
Inward rectification arises mainly from blockage of outward current by internal magnesium.
KCNJ13 exhibits low single-channel conductance, low sensitivity to external barium and cesium block, and no dependence of rectification on internal magnesium.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(이미지 파일: APC-125-AG-50UL_Kir7.1_KCNJ13_O70617-1_Rabbit.svg, APC-125-AG-50UL_Kir7.1_KCNJ13_O70617-1_Rabbit_PDP.jpeg)