Thermo Fisher Scientific Human MAP3K9 (MLK1), GST Tag Recombinant Protein
Human MAP3K9 (MLK1) 단백질로, GST 태그가 부착된 재조합 단백질입니다. MAP kinase 경로 연구용으로 사용되며, 세포 스트레스 및 신호전달 연구에 적합합니다. Insect cell에서 발현되었으며, 고순도 정제 상태로 제공됩니다.
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- pk
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Thermo Fisher Scientific Human MAP3K9 (MLK1), GST Tag Recombinant Protein
Applications
- Kinase Assay (KA)
Tested Dilution: Assay-dependent
Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Expression System | Insect cells |
| Amino Acid Sequence | 1–500 |
| Tag | GST-tag |
| Molecular Weight | 83.4 kDa |
| Class | Recombinant |
| Type | Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Purified |
| Storage Buffer | 50 mM Tris (pH 7.5), 2 mM DTT, 50% glycerol, 0.02% Triton X-100, 0.5 mM EDTA, 150 mM NaCl |
| Contains | No preservative |
| Storage Conditions | -80°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Dry ice |
Product Specific Information
- For maximum recovery, spin prior to use.
- Aliquots of 5 µg, 10 µg, and 20 µg sizes are not recommended; use from original packaging until exhausted.
- For larger sizes, aliquoting may reduce freeze/thaw cycles; aliquots below 20 µL are not recommended.
- Do not store kinase diluted.
- Properly stored at -80°C, guaranteed for 6 months from date of purchase.
Protein Form: Catalytic
Target Information
MAP3K9 (MLK1) is a serine/threonine protein kinase involved in the MAP kinase pathway. It acts as an upstream activator of the MKK/JNK signal transduction cascade by phosphorylating MAP2K4/MKK4 and MAP2K7/MKK7, which activate JNKs. The MKK/JNK signaling pathway regulates stress responses via activator protein-1 (JUN) and GATA4 transcription factors. MAP3K9 also contributes to mitochondrial death signaling, including cytochrome c release leading to apoptosis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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