Thermo Fisher Scientific Cystatin 2 Monoclonal Antibody (OTI2D6)
Cystatin 2 단백질을 인식하는 Mouse monoclonal antibody (OTI2D6). Western blot 및 Flow cytometry에 적합하며, Human 시료에 반응. Affinity 정제, PBS/BSA/glycerol buffer로 제공되며, 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D6 |
| Immunogen | Full length human recombinant protein of CST2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.59 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2723042 |
Target Information
The cystatin superfamily is a well-established family of cysteine protease inhibitors.
Cystatins A and B (type 1) are mainly intracellular; cystatins C, D, E/M, F, G, S, SN and SA are extracellular (type 2); and the kininogens are type 3 cystatins, which are intravascular proteins.
All true cystatins inhibit cysteine peptidases of the papain family, such as cathepsins, and some also inhibit legumain family enzymes.
Cystatin SA, S, and SN are primarily found in saliva, but S and SN can also be expressed in tears, urine, and seminal fluid.
Cystatin C is expressed in brain, thymus, ovary, epididymis, and vas deferens.
Cystatin D protects against proteinases in the oral cavity, while Cystatin E/M and F moderate the inhibition of cathepsin proteins.
The fetuins, part of the cystatin superfamily, are secretable proteins that influence osteogenesis, bone resorption, regulation of insulin and hepatocyte growth factor receptors, and the response to systemic inflammation.
High and low molecular weight kininogens (Kininogen HC and LC) both inhibit thrombin- and plasmin-induced aggregation of thrombocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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