Thermo Fisher Scientific TEAD1/2/3/4 Recombinant Rabbit Monoclonal Antibody (23GB4680)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:5,000

-

Immunocytochemistry (ICC/IF)

1:1,000

-

Flow Cytometry (Flow)

1:2,000

-

Product Specifications

Species Reactivity

Human, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293F

Class

Recombinant Monoclonal

Type

Antibody

Clone

23GB4680

Immunogen

A synthesized peptide derived from human TEAD1+TEAD2+TEAD3+TEAD4 (150-300AA). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TEAD1/2/3/4,uniProtId:P28347-1,ncbiNodeId:9606,antigenRange:150-300,antigenLength:426,antigenImageFileName:MA5-52728_TEAD1234_P28347-1_Rabbit.svg,antigenImageFileNamePDP:MA5-52728_TEAD1234_P28347-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2.5 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Target Information

TEAD1, TEAD2, TEAD3, and TEAD4 are members of the TEAD (TEA domain) family of transcription factors. These factors are known to play important roles in various biological processes, including development, cell proliferation, differentiation, and organogenesis.| TEAD1, TEAD2, TEAD3, and TEAD4 exhibit overlapping but also distinct expression patterns and functions. They are involved in diverse cellular processes and have been implicated in the regulation of embryonic development, tissue homeostasis, cell fate determination, and tumor progression. | TEAD proteins are known to interact with various co-factors, including the transcriptional co-activators YAP (Yes-associated protein) and TAZ (transcriptional co-activator with PDZ-binding motif), which play crucial roles in the Hippo signaling pathway. The interaction between TEAD and YAP/TAZ is essential for the activation of downstream target genes involved in cell proliferation and survival.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.