Thermo Fisher Scientific CD44var (v7-v8) Monoclonal Antibody (VFF-17), eBioscience
인간 CD44 변이형(v7-v8)을 특이적으로 인식하는 단클론 항체로, Flow Cytometry, IHC, WB 등에 사용 가능. 마우스 IgG2b 형식의 비결합 항체이며, 순도 95% 이상. 세포 접착 및 이동 연구에 유용.
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Thermo Fisher Scientific CD44var (v7-v8) Monoclonal Antibody (VFF-17), eBioscience
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-Dependent | - |
| Immunohistochemistry (IHC) | Assay-Dependent | 1 publication |
| Immunocytochemistry (ICC/IF) | - | 1 publication |
| Flow Cytometry (Flow) | Assay-Dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | VFF-17 |
| Immunogen | Recombinant Human CD44var (v7-v8) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2–7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10596832 |
Additional Formats
Product Specific Information
Specifically recognizes an epitope encoded by exons v7-v8 on the variant portion of human CD44.
Standard CD44 (CD44s) lacks the variable region and is mainly found in lymphohematopoietic cells.
Multiple isoforms (CD44v1–CD44v11) arise from alternative splicing within the extracellular domain.
Applications Tested: Flow Cytometry, Immunohistochemistry (Frozen), Western Blotting
Purity: >95%
Target Information
CD44 is a 100 kDa cell surface glycoprotein widely expressed on human leukocytes, brain white matter, and some epithelial cells of the intestine and breast.
It acts as a receptor for hyaluronic acid (HA) and mediates cell-cell interactions, adhesion, and migration.
CD44 participates in lymphocyte activation, recirculation, and homing, and its expression may be up-regulated in certain carcinomas, potentially linked to metastatic potential.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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