Thermo Fisher Scientific CD5 Monoclonal Antibody (UMAB9), UltraMAB

Applications and Tested Dilution

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

CD5 is a 67 kDa human T-lymphocyte single-chain transmembrane glycoprotein. It is present on all mature T-lymphocytes, most thymocytes, and many T-cell leukemias and lymphomas.
CD5 also reacts with a subpopulation of activated B-cells and may act as a receptor regulating T-cell proliferation.
It is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T-cell areas.
CD5 expression is associated with T-cell leukemia, lymphomas, and activated T cells.
Diseases linked to CD5 dysfunction include thymus cancer and Richter’s Syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.