Merck Anti-α Actinin antibody, Mouse monoclonal

Anti-α Actinin antibody, Mouse monoclonal

clone BM-75.2, purified from hybridoma cell culture

Alpha-actinin cytoskeletal isoform, F-actin cross-linking protein, Non-muscle alpha-actinin-1, Alpha-actinin-1

생물학적 소스

mouse

항체 형태

purified from hybridoma cell culture

antibody product type

primary antibodies

클론

BM-75.2, monoclonal

분자량

~100 kDa

species reactivity

human

포장

antibody small pack of 25 μL

농도

~1 mg/mL

technique(s)

immunoblotting: 0.5-1 μg/mL using human HeLa cells extract.
immunofluorescence: 5-10 μg/mL using human foreskin fibroblast Hs68 cells.

동형

IgM

UniProt 수납 번호

P12814

배송 상태

dry ice

저장 온도

−20°C

Gene Information

human ... ACTN1(87)

Monoclonal Anti- α Actinin (mouse IgM isotype) is derived from the hybridoma BM-72.5 produced by the fusion of mouse myeloma cells and splenocytes from mice immunized with a cytoskeletal fraction of bovine mammary gland epithelium (BMGE) cultured cells. α-Actinin is an actin binding protein present in both muscle and non-muscle cells. It has a molecular weight of 100,000 daltons and forms dimers in solution. In normal skeletal muscle, α-actinin is associated with the z-discs that define muscle sarcomeres. In smooth muscle, α-actinin has been detected in dense bodies and plaques characteristic of the tissue.