Merck Anti-Calcineurin (α-Subunit) antibody, Mouse monoclonal

Anti-Calcineurin (α-Subunit) antibody, Mouse monoclonal

clone CN-A1, purified from hybridoma cell culture

Calmodulin-dependent calcineurin A subunit alpha isoform, CAM-PRP catalytic subunit, Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform

생물학적 소스

mouse

항체 형태

purified from hybridoma cell culture

antibody product type

primary antibodies

클론

CN-A1, monoclonal

species reactivity

human, bovine, rat

포장

antibody small pack of 25 μL

농도

~1 mg/mL

technique(s)

immunoblotting: 1.25-2.5 μg/mL using mouse or rat brain tissue extract.

동형

IgG1

UniProt 수납 번호

Q08209

배송 상태

dry ice

저장 온도

−20°C

Gene Information

bovine ... PPP3CA(286852)
human ... CALNA(5530)
rat ... Caln1(363909)

Calcineurin (a-subunit) (CnA), also known as Serine/threonine-protein phosphatase 2B catalytic subunit alpha (PP3CA), Calmodulin-dependent calcineurin A subunit alpha (CALN/CALNA) or CAM-PRP catalytic subunit, is a major soluble calmodulin-binding protein in the brain. Calcineurin is a heterodimer metalloenzyme, Ca2+/Calmodulin dependent serine/threonine protein phosphatase 3 (PPP3), with a relatively narrow substrate specificity4-6,8 It is composed of two subunits, a catalytic calmodulin-binding a subunit (61 kDa, calcineurin A [CnA]) and regulatory calcium-binding ß subunit (18 kDa, calcineurin B [CnB]).6,7 Both subunits are highly conserved from yeast to mammals.8