Merck Anti-SNF2β/BRG1 Antibody

Anti-SNF2β/BRG1 Antibody

serum, Upstate®

Probable global transcription activator SNF2L4, ATP-dependent helicase SMARCA4, SNF2-beta, BRG-1, Mitotic growth and transcription activator, Brahma protein homolog 1, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A m

생물학적 소스

rabbit

Quality Level

100

항체 형태

serum

antibody product type

primary antibodies

클론

polyclonal

species reactivity

rat, mouse, human

포장

antibody small pack of 25 μL

manufacturer/tradename

Upstate®

technique(s)

immunoprecipitation (IP): suitable
western blot: suitable

동형

IgG

NCBI 수납 번호

NM_003072

UniProt 수납 번호

P51532

배송 상태

ambient

Gene Information

human ... SMARCA4(6597)

The SWI-SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF2α) and Brg-1 (also designated SNF2β) are the ATPase subunits of the mammalian SWI-SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI-SNF complex. Addition of Ini1, BAF155 and BAF170 to Brg-1 appears to increase remodeling activity. Other complex subunits are thought to play regulatory roles. hSNF2L and hSNF2H both appear to be homologs of Drosophila ISWI, a Brm related ATPase that is present in chromatin remodeling complexes other than SWI/SNF, including the NURF (nucleosome remodeling factor).