Merck Anti-EEA1 Antibody

Anti-EEA1 Antibody

from rabbit, purified by affinity chromatography

early endosome antigen 1, early endosome-associated protein, early endosome antigen 1, 162kD, Endosome-associated protein p162, Zinc finger FYVE domain-containing protein 2

생물학적 소스

rabbit

Quality Level

100

항체 형태

affinity isolated antibody

antibody product type

primary antibodies

클론

polyclonal

정제법

affinity chromatography

species reactivity

human, mouse

포장

antibody small pack of 25 μL

technique(s)

immunocytochemistry: suitable
western blot: suitable

NCBI 수납 번호

NP_003557

UniProt 수납 번호

Q15075

배송 상태

ambient

Gene Information

human ... EEA1(8411)

Early endosome antigen 1 (EEA1) is a 170 kDa coiled-coil protein belonging to a group of early endosomal Rab5 effector proteins. EEA1 has a putative role in the tethering/docking of endocytic vesicles prior to their fusion with early endosomes. This protein is characterized as containing a zinc finger-like domain and coiled-coil regions. The zinc finger-like domain, also known as the FYVE finger, is a motif rich in cystine, is a necessary component of EEA1’s ability for endosomal targeting, and is specifically known for its dual interaction with Rab5 GTPase and phosphotidylinositol 3-phosphate (Ptdlns-3-P).