Merck Anti-GLUT1 (CT) Antibody, clone 5B12.3

Anti-GLUT1 (CT) Antibody, clone 5B12.3

clone 5B12.3, from mouse

Solute carrier family 2 facilitated glucose transporter member 1, Glucose transporter type 1,erythrocyte/brain, GLUT-1, HepG2 glucose transporter

Quality Level

100

생물학적 소스

mouse

항체 형태

purified immunoglobulin

antibody product type

primary antibodies

클론

5B12.3, monoclonal

species reactivity

rat, human

포장

antibody small pack of 25 μL

technique(s)

immunohistochemistry: suitable
western blot: suitable

동형

IgG1κ

NCBI 수납 번호

NP_006507

UniProt 수납 번호

P11166

배송 상태

ambient

저장 온도

2-8°C

Gene Information

human ... SLC2A1(6513)

GLUTs (Glucose transporters) are a family of integral membrane proteins that facilitative glucose uptake by cells. They are integral membrane glycoproteins involved in transporting glucose into most cells. Seven types of glucose transport carrier proteins, designated as GLUT 1 to 7, facilitate glucose transport across the cell membrane. Molecular cloning of glucose transporters have identified a family of closely related genes that encode at least 7 proteins exhibiting high degree of amino acid homology (45% to 65%), all in the molecular weight range of 40 to 60 kDa. GLUT1 functions in constitutive or basal glucose uptake in adult tissues and is the predominant glucose transporter in embryonic and fetal tissues. It has two forms, a 55 kDa and a 45 kDa. The 55 kDa form of GLUT1 regulates import of glucose from blood to brain across the endothelial cells of the blood-brain barrier (BBB), whereas the 45 kDa form of GLUT1 predominantly regulates nonvascular glial glucose uptake.