Merck Anti-Myosin Light Chain Kinase antibody, Mouse monoclonal

Anti-Myosin Light Chain Kinase antibody, Mouse monoclonal

clone K36, purified from hybridoma cell culture

Smooth muscle, MLCK, Kinase-related protein (KRP), Myosin light chain kinase, Telokin, smMLCK

생물학적 소스

mouse

항체 형태

purified from hybridoma cell culture

antibody product type

primary antibodies

클론

K36, monoclonal

form

buffered aqueous solution

분자량

~160 kDa

species reactivity

turkey, bovine, pig, mouse, chicken, human

포장

antibody small pack of 25 μL

농도

~1 mg/mL

technique(s)

immunoblotting: 0.25-0.5 μg/mL using chicken gizzard extract

동형

IgG2b

UniProt 수납 번호

Q15746

배송 상태

dry ice

저장 온도

−20°C

Myosin Light Chain Kinase (MLCK) also known as MYLK is a Ca2+/calmodulin dependent myosin light chain phosphorylating agent. This enzyme plays a major role in the phosphorylation of the regulatory light chains of myosin which are essential for the shortening and tension development of smooth muscle cells resulting in smooth muscle contraction. Myosin light chain kinase are widely expressed in many different tissues and cells of eukaryote species. There are two genes mylk1 and mylk2 encoding the MLCK protein, mylk2 is exclusively expressed in skeletal muscle cells.