Merck Anti-Mn-SOD Antibody

Anti-Mn-SOD Antibody

Upstate®, from rabbit

Mn superoxide dismutase, indophenoloxidase B, manganese superoxide dismutase, manganese-containing superoxide dismutase, mangano-superoxide dismutase, superoxide dismutase 2, mitochondrial

생물학적 소스

rabbit

Quality Level

100

항체 형태

purified immunoglobulin

antibody product type

primary antibodies

클론

polyclonal

species reactivity

human, bovine, rat, mouse

should not react with

canine

포장

antibody small pack of 25 μg

manufacturer/tradename

Upstate®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
western blot: suitable

동형

IgG

NCBI 수납 번호

NP_000627

UniProt 수납 번호

P04179

배송 상태

ambient

Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS). SOD catalyzes the dismutation reaction of superoxide radical anion (O2-) to hydrogen peroxide, which is then catalyzed to innocuous O2 and H2O by glutathione peroxidase and catalase. Several classes of SOD have been identified. These include intracellular copper, zinc SOD (Cu, Zn SOD/SOD1), mitochondrial manganese SOD (Mn SOD/SOD2) and extracellular Cu, Zn SOD (EC SOD/SOD3). The manganese containing 80 kDa tetrameric enzyme SOD2 is located in the mitochondrial matrix in close proximity to a primary endogenous source of superoxide, the mitochondrial respiratory chain.