Anti-Claudin-5 Antibody
from rabbit, purified by affinity chromatography
Claudin-5, Transmembrane protein deleted in VCFS, TMDVCF
생물학적 소스
rabbit
Quality Level
항체 형태
affinity isolated antibody
antibody product type
primary antibodies
클론
polyclonal
정제법
affinity chromatography
species reactivity
mouse, rat, horse, human
species reactivity (predicted by homology)
equine (based on 100% sequence homology), ox (based on 100% sequence homology)
포장
antibody small pack of 25 μg
technique(s)
immunohistochemistry: suitable (paraffin)
western blot: suitable
NCBI 수납 번호
UniProt 수납 번호
배송 상태
ambient
저장 온도
2-8°C
Claudin-5, a transmembrane protein deleted in velo-cardio-facial syndrome (TMVCF), seems to be involved in endothelial tight junctions. Claudin-5 has been exclusively found in the cell-cell borders of endothelial cells. Lower claudin-5 levels in sinusoidal endothelial cells could lead to their dysfunction during liver injuries. Levels of claudin-5 in tumor vessels could be a potential marker for hepatocellular carcinoma prognosis. The loss of claudin-5 function has been linked to carcinogenesis.
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